Wilms tumour is the most common kidney cancer in children. In most cases this tumour is localized in one kidney but less commonly has spread to other parts of the body such as the lungs or involves both kidneys at the same time. The treatment involves biopsy, CT scan of the chest to look for any tumour spread, administration of chemotherapy for approximately a month (Vincristine, Actinomycin-D, sometimes Doxorubicin), surgery and depending on the findings and the stage of tumour further chemotherapy (Vincristine, Actinomycin-D, sometimes Doxorubicin, Carboplatin, Cyclophosphamide) with or without radiation therapy.

The prognosis is excellent. For the patients who experience re-growth of their tumour depending on the initial therapy further surgery, chemotherapy, and radiotherapy can be offered with fair prognosis.